Peripheral Arterial Insufficiency

[unable to retrieve full-text content] Functional testing nonsuperior to routine care for percutaneous coronary intervention patients    2 Minute Medicine

In adults, it is a complication and often the first clinical manifestation of ongoing ischaemic heart disease (i.e. a disease in which the heart is poorly supplied with blood, as typically occurs in angina pectoris and myocardial infarction). Sudden cardiac death is a far from rare event It alone is responsible for more than 50,000 deaths a year and is the cause of 50% of all deaths from heart disease. Causes and risk factors of sudden cardiac death Among the most important causes and risk factors for sudden cardiac death are a number of conditions and diseases ischaemic heart disease (the most common cause, approximately 9 out of 10 cases); congenital coronary malformations; mitral valve prolapse; myocarditis and endocarditis; dilated or hypertrophic cardiomyopathy (from chronic arterial hypertension); pulmonary hypertension; endocranial hypertension that may lead to pathological reflex bradycardia; acquired or inherited alterations of the conduction sys

Abstract Intestinal ischemia–reperfusion (IIR) is a life-threatening clinical event with damaging signals whose origin and contents are unclear. Here we observe that IIR significantly affect the metabolic profiles of most organs by unbiased organ-wide metabolic analysis of gut contents, blood, and fifteen organs in rats ( n  = 29). Remarkably, correlations between gut content metabolic profiles and those of other organs are the most significant. Gut contents are also the only ones to show dynamic correlations during IIR. Additionally, according to targeted metabolomics analysis, several neurotransmitters are considerably altered in the gut during IIR, and displayed noteworthy correlations with remote organs. Likewise, metagenomics analysis ( n  = 35) confirm the effects of IIR on gut microbiota, and identify key species fundamental to the changes in gut metabolites, particularly neurotransmitters. Our multi-omics results establish key roles of gut contents in IIR induced remote injury

[unable to retrieve full-text content] Skin Cancer Rash: How to Identify Skin Cancer vs. a Rash    Healthgrades

Contact dermatitis (rashes on the skin), tiny bumps, and hives are all signs of an allergic reaction. While these symptoms might not bother you on other parts of your body, they can be difficult to ignore on your face. In this article, you will learn about contact dermatitis on the face, how to spot an allergic reaction, and when to seek medical attention. iStock / Getty Images Plus What Are Allergies? Allergies develop when your immune system misfires, triggering a reaction to everyday substances instead of viruses or bacteria. These reactions result from your body recognizing an allergen as a foreign and unwanted substance. You can develop allergies to many different things, from pollens to pets. Some common allergens include: What's an allergic reaction? An allergic reaction is the body's response after exposure to an allergen. Your body makes antibodies against things it recognizes as harmful substances (alle

health Published on Sep 12, 2022 03:15 PM IST Is your child suffering from hand, foot and mouth disease? Watch out for these warning signs and follow these expert tips. Hand, foot and mouth disease: Watch out for these symptoms; dos and don'ts(Shutterstock) By Parmita Uniyal Hand, foot and mouth disease (HFMD) is in news these days with the rise in number of tomato flu cases in India, which is touted as another variant of HFMD. More common in children under 5, hand, foot and mouth disease is caused by the coxsackie group of viruses and is highly contagious. It can affect older children and adults too. Your kids may develop tongue ulcers, reddish rashes or elevated sores on palms and sores along with sore throat and fever. (Also read: Tomato flu: Know the common symptoms, prevention tips from experts) "It usually starts with a fever, poor appetite, a vague feeling of being unwell (malaise), and sore throat. One or

Allograft application of Regenative Labs AmnioText™ demonstrated to accelerate wound closure time.  PENSACOLA, Fla. , Sept. 22, 2022 /PRNewswire/ -- Regenative Labs, a leading HCT/P manufacturer, has authored a peer-reviewed case study outlining the benefits of dehydrated amniotic membrane allografts (DAMA) in the treatment of advanced venous leg ulcers caused by chronic venous insufficiency (CVI). Regenative Labs (PRNewsfoto/Regenative Labs) CVI is a lifelong, moribund, and debilitating disease with tremendous personal and financial costs. At its core, CVI involves blood pooling in the lower extremities secondary to inadequate venous blood return. As venous circulation slows, metabolic demands of the cells in the lower extremities increase, leading to stasis dermatitis, infection, cellular death, and venous ulceration. Treatment expenses can range from $20 for Neosporin and bandages to $80,000 for lower limb amputation. Regenative's study outlines a p

Hypothyroidism (low thyroid function) is a common hormonal condition. One in 300 people in the United States is diagnosed with hypothyroidism. Females and people over age 65 are the groups most often diagnosed with hypothyroidism. While there is no cure, treatment can restore hormone levels and reduce symptoms. This article will explore important facts and statistics about hypothyroidism, including how common it is; who it affects by race, sex, and age; its causes and risk factors; screening and early detection; and mortality. peakSTOCK / Getty Images Hypothyroidism Overview Hypothyroidism is a condition in which the thyroid gland (located at the front of the neck) does not produce enough thyroid hormones. Thyroid hormones are responsible for the body's metabolism (the way it uses energy) and major functions (such as heart rate). Without enough thyroid hormones, the body's functions slow down, causing a variety of symptoms. While symp