Peripheral Arterial Insufficiency

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A recently published randomized clinical trial (NCT03574038) showed that high-definition cathodal direct current stimulation (HD C-tDCS) was safe in patients with acute ischemic stroke (AIS), with signals of beneficial effect upon penumbral salvage. Investigators concluded that the findings warrant testing in larger multicenter trials. Led by Mersedeh Bahr Hosseini, MD, a neurologist at UCLA Health, the first-in-human pilot study included 10 patients, 7 of which were randomized to active treatment and 3 to sham. HD C-tDCS was delivered to the ischemic tissue using 6 individualized montages. These montages were predesigned to cover 6 vascular distribution-specific ischemic fields caused by occlusions of the middle cerebral artery (MCA) trunk, MCA superior division, MCA inferior division, posterior cerebral artery, anterior cerebral artery, and posterior inferior cerebellar artery. Patients included were within 24 hours from AIS onset, had imaging evidence of cortical ischemic, a presenc

Those wanting to get a leg up on their heart health should pay attention to pain in their lower limbs. While some may chalk up pain in their calves from walking to aging or muscle strain, it could be a symptom of peripheral arterial disease. PAD can lead to serious complications such as heart attack, stroke or critical limb ischemia, which causes tissues to die during injury or infection, according to the Mayo Clinic. PAD is often caused by a buildup of fatty, cholesterol-containing deposits that buildup in the arteries. This process, called atherosclerosis, reduces blood supply to the leg muscles which can lead to pain and cramping. As many as 6.5 million people aged 40 and older have PAD in the US, according to the CDC. Risk factors for PAD include smoking, high blood pressure, atherosclerosis, diabetes, high cholesterol and being over 60 years old.  A pain in your leg could be a warning sign for a d

[unable to retrieve full-text content] Sudden cardiac arrest in young athletes is rare and hard to predict    UCHealth Today

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Ice-cold, locally brewed beer is a staple in a Milwaukeean's diet. It's part of the culture. However, beer is rich with organic chemicals, called purines, that can crystalize and accumulate in the blood, which could lead to gout and cardiovascular disease. A study estimated that between 2015 and 2016, 9.2 million people in the United States experienced gout. And cardiovascular disease continues to be the leading cause of death for people over 45. But don't say goodbye to your favorite craft beer just yet. New research from the University of Wisconsin-Madison and international collaborators discovered certain bacteria that can break down those inflammatory chemicals in the gut, which, in turn, can reduce the amount of chemicals that circulate in the blood. Purines are not inherently bad. They are a natural compound that cells need to build DNA and RNA. High levels of purine, though, are harmful. When purines are metabolized, they generate a waste product called uric acid. Mo

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Image credit Peter Phiri and Gayathri Delanerolle, Southern Health NHS Foundation Trust Authors: Gayathri Delanerolle 1,2 , Vikram Sinai Talaulikar 2 , Peter Phiri 1,2,4 , Ashish Shetty 2 1 Digital Evidence Based Medicine Lab 2 Southern Health NHS Foundation Trust 3 University College London 4 University of Southampton Menopause is a natural process that impacts women and transgender individuals. Menopausal symptoms vary vastly although hot flushes, night sweats, sleep disturbance, mood changes and cognitive issues such as ' brain fog' that could impact concentration are commonly reported. For some, these symptoms are mild and short lived whilst for others these can be persistent and severe. It is unclear whether cognitive symptoms during menopausal transition indicate a future increased risk of dementia. It is vital to note that not everyone with m

Intense exercise may increase stroke risk among patients with moderate or severe stenosis, new research suggests. Investigators simulated blood flow in a sophisticated computational model of the internal carotid artery (ICA) at three stages of stenosis ― without blockage, with mild (30%) blockage, and with moderate (50%) blockage. They compared the effect of exercise-induced elevated heart rate (140 bpm) to that of two resting heart rates (67 and 100 bpm). As expected, intense exercise was beneficial for the patients with healthy arteries and for those with mild stenosis, but it showed potential for adversely affecting arteries among patients with moderate or higher levels of stenosis because it increased the arterial wall shear stress (WSS) at the stenosis zone. "Increased shear stress at the stenosis zone may lead to the rupture of stenosis, and the ruptured plaque then may go directly to the brain through the ICA by blocking t

wellcare medicare :: Article Creator Wellcare Medicare Advantage Review In 2023 "Wellcare Medicare Advantage zero premium plans are the most popular," says Melissa Spangler, a Wellcare pre-enrollment specialist. If you choose a Wellcare Medicare Advantage zero premium plan, you won't pay a monthly premium for your coverage, but you will still need to pay the standard 2023 Medicare Part B premium of $164.90 per month. You'll also pay for your health care services as you need them, meaning your annual medical expenses will depend on how much care you need. If you need medical care often or if your health care providers don't accept Wellcare Medicare Advantage, the cost of your health care could become expensive quickly. Wellcare Medicare Advantage Plans typically include prescription drug coverage as well. To determine whether a Wellcare Medicare Advantage plan is right for you, start by considering if the plan's drug f

A Bendigo nurse is on a mission to raise awareness of fibromuscular dysplasia (FMD) after losing her only sister to the rare disease and receiving her own life-changing diagnosis. Key points: Cristy Spencer was 44 when she died suddenly from fibromuscular dysplasia FMD causes the progressive twisting of the blood vessels throughout the body Her sister, Karena, has also been diagnosed with the disease, which is more common in women Former triathlete Karena Spencer can no longer train or compete and feels like "a ticking time bomb" since she was also diagnosed with FMD.  FMD is a vascular disease that causes abnormalities in the arteries of the body and is linked to stroke and heart attacks. In 2021, Ms Spencer lost her 44-year-old sister Cristy following complications from a stroke, which was later discovered to be linked to FMD. "Cristy was a very community-minded person in Melbourne working from hom

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Share on Pinterest Heart health may be affected by certain gut bacteria, researchers say. lynnebeclu/Getty Images Certain bacteria in the gut, especially some species of strep normally found in the mouth and digestive tract, may affect heart health. In particular, researchers say, gut bacteria may be linked to a build-up of plaque that can lead to clogged arteries. Experts say the new findings build on previous research that indicates a link between gut bacteria and cardiovascular health. Some heart problems may begin in the mouth and gut, a new study suggests. Atherosclerotic plaques — commonly known as clogged arteries — are deposits of fat, cholesterol, and other substances that are a major cause of heart attacks. A higher occurrence of these plaques is associated with the presence of certain oral bacteria in the gut — particularly Streptococcus bacteria — according to Swedish researchers. The study, led by researchers at Uppsala and Lund University and published in the journal Ci

coronary artery d :: Article Creator Adults With Coronary Artery Disease Not Meeting Cholesterol Targets FRIDAY, July 7, 2023 (HealthDay News) — Most adults with coronary artery disease (CAD) do not meet low-density lipoprotein cholesterol (LDL-C) targets, according to a research letter published in the July 3 issue of the Journal of the American Medical Association. Rahul Aggarwal, M.D., from Brigham and Women's Hospital in Boston, and colleagues used data from the National Health and Nutrition Examination Survey (January 2015 to March 2020) to assess lipid control among 25,531 U.S. Adults (≥20 years) with reported CAD. The researchers found that among adults with reported CAD, 67.9 percent were receiving statin therapy and 6.4 percent were receiving ezetimibe. Age-adjusted mean LDL-C was 94.4 mg/dL, with 73.5 percent of participants having an LDL-C level ≥70 mg/dL. Among adults with reported CAD receiving statin therapy, 4.2 percent also r