Peripheral Arterial Insufficiency

[unable to retrieve full-text content] The ALPHA phase 1 study: pulmonary ArteriaL hypertension treated with CardiosPHere-Derived allogeneic stem cells    ScienceDirect.com

Abstract Revised cardiac risk index (RCRI) is widely used for surgical patients without containing age as a risk factor. We investigated age older than 65 years with respect to low-to-moderate risk of RCRI. From January 2011 to June 2019, a total of 203,787 consecutive adult patients underwent non-cardiac surgery at our institution. After excluding high-risk patients defined as RCRI score > 2, we stratified the patients into four groups according to RCRI and age (A: age < 65 with RCRI < 2, [ n  = 148,288], B: age ≥ 65 with RCRI < 2, [ n  = 42,841], C: age < 65 with RCRI = 2, [ n  = 5,271], and D: age ≥ 65 with RCRI = 2, [ n  = 5,698]). Incidence of major cardiac complication defined as a composite of cardiac death, cardiac arrest and myocardial infarction was compared. After excluding 1,689 patients with high risk (defined as RCRI score > 2), 202,098 patients were enrolled. The incidence with 95% confidence interval of major cardiac complicatio...

[unable to retrieve full-text content] Acute total occlusion of the common femoral artery as a consequence of COVID-19 pneumonia resulting in hip joint ...    ScienceDirect.com

About half of all heart attacks are mistaken for less serious problems and can increase your risk of dying from coronary artery disease.   Image: goir/Getty Images You can have a heart attack and not even know it. A silent heart attack, known as a silent myocardial infarction (SMI), account for 45% of heart attacks and strike men more than women. They are described as "silent" because when they occur, their symptoms lack the intensity of a classic heart attack, such as extreme chest pain and pressure; stabbing pain in the arm, neck, or jaw; sudden shortness of breath; sweating, and dizziness. "SMI symptoms can feel so mild, and be so brief, they often get confused for regular discomfort or another less serious problem, and thus men ignore them," says Dr. Jorge Plutzky, director of the vascular disease prevention program at Harvard-affiliated Brigham and Women's Hospital. For instance, men may feel fatigue or physical discomfort and c...

While on vacation with his wife last year, Peter Sunwoo heard about a healthy acquaintance who had a heart attack at 39 years old. He and a friend had just turned 40, so they decided to get their hearts checked — just in case. Sunwoo's doctor appointment led to an early discovery of five extremely blocked arteries, and he underwent surgery to repair them before they caused a heart attack. His doctors couldn't point to a specific cause for the blockages, and Sunwoo didn't have any risk factors, so they speculated that it was likely genetic. "Luckily, I found out just by chance," Sunwoo, 41, of Brooklyn tells TODAY.com. "I'm an extremely unlucky person for even having this genetic thing, but at the same time, it's being countered with being extremely lucky because my heart is in complete, functional condition." A check-up reveals an unknown problem For much of his life, when Sunwoo ran, he felt a tightness in his chest. He thought running...

Last Thanksgiving, Cynthia Mosson had been on her feet all day in her kitchen in Frankfort, Ind., preparing dinner for nine. She was nearly finished — the ham in the oven, the dressing made — when she suddenly felt the need to sit down. "I started hurting in my left shoulder," said Ms. Mosson, 61. "It got really intense, and it started to go down my left arm." She grew sweaty and pale and told her family, "I think I'm having a heart attack." An ambulance sped her to a hospital where doctors confirmed that she had suffered a mild heart attack. They said testing revealed serious blockages in all her coronary arteries and told her, "You're going to need open-heart surgery," Ms. Mosson recalled. When such patients head into an operating room, what happens next has a lot to do with their sex, a recent study in JAMA Surgery reported. The study reinforced years of research showing that male and female patients can have very different outcomes fo...

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