Peripheral Arterial Insufficiency

Introduction Coronary artery disease (CAD) remains one of the leading causes of cardiovascular morbidity and mortality worldwide. Despite the identification of modifiable risk factors and the development of risk prediction models that enable recognition of individuals at greater risk of future events, CAD risk evaluation still lacks accuracy in daily clinical practice. 1,2 In this regard, investigating novel risk factors is of great clinical importance in improving CAD risk prediction, thus leading to better patient care. Uric acid is the metabolic end product of purine metabolism in humans, which is under the control of the enzyme xanthine oxidase. 3 Although a wealth of research has reported that greater serum uric acid (SUA) levels are associated with poorer survival in patients with CAD, 4–7 several recent studies have failed to establish such an association. 8,9 Apart from the differences in study design, clinical backgrounds, adjustment of confounders, length of follow-

Microvascular ischemic brain disease describes conditions that affect the small blood vessels in the brain. These conditions include stroke, cerebral hemorrhage, and dementia. Age, high blood pressure, and diabetes are among the primary risk factors for microvascular ischemic brain disease. Microvascular ischemic disease can also occur in other organs, including the heart, kidney, or eyes. In this article, we provide more information on microvascular ischemic brain disease, including its symptoms, causes, and treatment. Doctors use the term microvascular ischemic disease to refer to changes that occur in the walls of the small blood vessels of an organ. Conditions that affect these blood vessels can damage white matter in the brain. White matter contains nerve fibers that send signals between different parts of the brain. Microvascular ischemic brain disease is a "silent" disease, which means that most people who have it do not experience noticeable symptoms. However, doctors

A new study has found that people with chronic obstructive pulmonary disease (COPD) experience cardiac autonomic dysfunction , meaning that the heart's ability to speed up during exercise and recover afterwards is limited, regardless of disease severity. The study, published in Annals of Physical and Rehabilitation Medicine , was led by the Barcelona Institute for Global Health ( ISGlobal ) , a centre supported by the "la Caixa" Foundation. "Although it is a respiratory disease, COPD also affects other systems of the body," commented Laura Delgado , predoctoral researcher at ISGlobal. "Its effect on the cardiovascular and muscular system has been extensively studied, but its effect on the autonomic nervous system has received less attention." With Delgado as lead author, the researchers set out to study this effect. The study assessed participants' ability to increase their heart rate

Eczema is a condition that causes areas of itchy skin with a rash-like appearance. It can appear anywhere on the body, including on the nipples. Eczema can cause red, scaly rashes around the nipple that can be itchy. In some cases, more serious conditions may look similar to nipple eczema. This article discusses what eczema is, how it affects the nipples, and other conditions that are similar to nipple eczema. Eczema refers to a group of skin conditions that affect 1 in 10 people and cause areas of itchy, inflamed skin. Irritants and allergens can cause eczema symptoms. It can occur at any age and appear anywhere on the skin, including the nipples. Symptoms of nipple eczema affect each person differently and vary in severity. Nipple eczema develops on the areola, which is the area of dark skin surrounding the nipple. People with nipple eczema may notice an itchy, scaly, or dry rash around one or both nipples. The skin may also swell, ooze, or feel rough and leathery. People with eczema

Each product we feature has been independently selected and reviewed by our editorial team. If you make a purchase using the links included, we may earn commission. Cozy sweaters, crackling fireplaces, and holidays that bring people together are some of the best parts of wintertime. The dry skin that cold weather brings along with it is one of the worst. Growing up in the desert and now living in the northeast, I'm no stranger to cracked, dry hands during the winter months. I've tried countless lotions and creams, but my current favorite has them all beat.  Curél released its Extreme Dry Hand Relief hand cream last year, and once I got my hands on a sample (pardon the pun), I couldn't get enough of it. A small dollop of the lotion goes a long way and quickly absorbs into the skin. But what's most impressive to me is that it doesn't leave behind an oily residue on your hands once it's properly rubbed in. That way, you can get back to whatever you we

Rashes can cause irritation and discomfort. Rashes in very visible places such as your hands or face might even cause embarrassment. Fortunately, most rashes are mild and not a cause for concern. You can generally treat a rash with over-the-counter (OTC) remedies. However, there are rashes that a medical professional should look at. These rashes might be a sign of an infection, allergic reaction, or disease. You can read 12 common signs a rash might be a sign of something more serious below. An area on your skin that is itchy, irritated, and swollen is called a rash. A rash can be raised, bumpy, blistered, or patchy. Rashes can present differently depending on your skin tone. People with lighter skin often see rashes that are pink, red, or purple. People with darker skin might develop rashes that are white, gray, or darker than the surrounding skin. Rashes can be caused by many things including: underlying health conditions stress sun exposure allergic reactions weather Rashes are very

New York, NY (November 04, 2021) Use of a novel technique called the quantitative flow ratio (QFR) to precisely identify and measure the severity of artery blockages can lead to significantly improved outcomes after percutaneous coronary intervention (PCI), according to a new study done in collaboration with Mount Sinai faculty. This research, which is the first to analyze QFR and its associated clinical outcomes, may lead to widespread adoption of QFR as an alternative to angiography or pressure wires to measure the severity of blockages, or lesions, in patients with coronary artery disease. The study results were announced on Thursday, November 4, as a late-breaking clinical trial at the Transcatheter Cardiovascular Therapeutics Conference (TCT 2021), and simultaneously published in The Lancet. "For the first time we have clinical validation that lesion se

Microvascular ischemic brain disease describes conditions that affect the small blood vessels in the brain. These conditions include stroke, cerebral hemorrhage, and dementia. Age, high blood pressure, and diabetes are among the primary risk factors for microvascular ischemic brain disease. Microvascular ischemic disease can also occur in other organs, including the heart, kidney, or eyes. In this article, we provide more information on microvascular ischemic brain disease, including its symptoms, causes, and treatment. Doctors use the term microvascular ischemic disease to refer to changes that occur in the walls of the small blood vessels of an organ. Conditions that affect these blood vessels can damage white matter in the brain. White matter contains nerve fibers that send signals between different parts of the brain. Microvascular ischemic brain disease is a "silent" disease, which means that most people who have it do not experience noticeable symptoms. However, doctors

If you have coronary artery disease (CAD), it means the arteries that supply blood to your heart muscle have plaque in their walls that may cause blockages. Getting those arteries to widen and become flexible again might seem daunting, but you're far from powerless. You can absolutely prevent CAD from worsening, and with some hard work, you might even be able to reverse some of the damage, says Gregg Fonarow, MD. He's the co-director of the UCLA Preventative Cardiology Program at the David Geffen School of Medicine and a spokesperson for the American Heart Association. CAD is the most common type of heart disease and the leading killer in the U.S. of both men and women. By taking action, you can reduce the chances of having a heart attack, which may happen if the plaque that's lining your arteries blocks blood flow to the heart. To protect yourself, you'll need to stay on top of your diet and exercise and take your medications every day, says Fonarow. If your goal is to

Lupus is a chronic autoimmune disorder that causes the immune system to attack healthy tissue in the body. Many people with lupus may experience a malar rash that extends over the face in the shape of a butterfly. Lupus is an autoimmune disease that affects at least 5 million people worldwide. However, the condition is more common in African American people. Females are also more likely to get lupus than males, and it occurs most often in those aged between 15–45 years. Lupus can cause many symptoms, including skin rashes, joint swelling, and headaches. Another common symptom is a malar rash, or butterfly rash, on the face. Lupus may also cause sores to appear on the skin. This article explores the symptoms and prevalence of lupus on black skin, along with causes and treatment options. Symptoms of lupus may include : malar rash, which appears as a butterfly-shaped red or different color rash across the cheeks and nose, that may feel painful or itchy a raised, scaly rash on the skin so