Peripheral Arterial Insufficiency

Abstract Cardiopoietic stem cells have reached advanced clinical testing for ischemic heart failure. To profile their molecular influence on recipient hearts, systems proteomics was here applied in a chronic model of infarction randomized with and without human cardiopoietic stem cell treatment. Multidimensional label-free tandem mass spectrometry resolved and quantified 3987 proteins constituting the cardiac proteome. Infarction altered 450 proteins, reduced to 283 by stem cell treatment. Notably, cell therapy non-stochastically reversed a majority of infarction-provoked changes, remediating 85% of disease-affected protein clusters. Pathway and network analysis decoded functional reorganization, distinguished by prioritization of vasculogenesis, cardiac development, organ regeneration, and differentiation. Subproteome restoration nullified adverse ischemic effects, validated by echo-/electro-cardiographic documentation of improved cardiac chamber size, reduced QT prolongation and augm

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pulmonary artery carries :: Article Creator What To Know About Pulmonary Embolism? A pulmonary embolism is a blockage in the pulmonary artery that supplies blood to the lungs. The blockage, usually caused by a blood clot, impairs oxygenation of the blood and can damage the heart. This means it can be life threatening. The word "embolism" comes from the Greek émbolos, meaning "stopper" or "plug." In a pulmonary embolism, the embolus forms in one part of the body and circulates throughout the blood supply. It then blocks the blood flowing through a vessel in another part of the body, namely the lungs. Blood clots often develop in the leg, which is called deep vein thrombosis (DVT). This article lists the symptoms of pulmonary embolism and outlines its diagnosis and treatment options. Although the exact number of those affected by pulmonary embolism or DVT is unknown, it may affect as many as 900,00

attack symptoms :: Article Creator Signs And Symptoms Of An Asthma Attack Medically reviewed by Susan Russell, MD An asthma attack is an episode where you experience a worsening of asthma symptoms. Asthma is a chronic lung disease that causes inflamed and narrowed airways, making breathing difficult. Symptoms of asthma include coughing, wheezing, shortness of breath, and chest tightness. These symptoms worsen during an asthma attack, which can be triggered by an allergen, strenuous exercise, or an upper respiratory infection like the common cold. During an asthma attack, the muscles surrounding your airways constrict (become narrower) and spasm, and mucus production in the airways increases. This makes it difficult to get air into your lungs. An asthma attack can be a terrifying experience—you may feel like there is a heavy weight on your chest or as if you are breathing through a straw as you struggle to bring in enough air. Asthma attack s

apple watch heart attack alert :: Article Creator 7 Ways To Check And Improve Heart Health With Apple Watch Want to go further with your Apple Watch health features or revisit important metrics you haven't tracked in a while? Follow along for a look at 7 valuable ways you can check and improve heart health with Apple Watch. Whether you've recently gotten an Apple Watch, are considering one, or have had one for years, you should be able to find some useful features to check and improve your heart health in our round-up. High and low heart rate notifications If you'd like an alert when your heart rate dips below or rises above a certain threshold and remains there for 10 minutes while inactive, this feature is available for those 13 years old and up. If you didn't turn it on the first time opening the Heart Rate app or want to change it: Open the Watch app on your iPhone Swipe down and choose Heart (under the My Watch tab)